The article is a general presentation of the Apostolic Constitution Praedicate Evangelium. After an introduction on the historical evolution of the Roman Curia, the author considers the basic inspiration of the current reform, which is to be understood as falling within the intent by Pope Francis of reforming of the Church as such. The first and fundamental aspect of this reform is the missionary spirit of the Curia, a reflection of the missionary nature of the whole Church, which is called to commit herself ever more deeply to evangelization in the face, on the one hand, of the secularization of the peoples in whom the Church has been present for centuries and who have lost the sense of God, and, on the other hand, in the face of the ever present need to proclaim Christ to peoples who have never known him. Another prevalent strand of thought is that of communion, synodality and proper decentralization, to which the principle of participation is linked. An element that is highlighted and that reveals the nature of the Roman Curia is that of its ministerial and vicarious character, which entails that those who are in charge in the Dicasteries, to whatever category of the faithful they belong, including that of the laity, always act by the vicarious authority of the Pope and not by their own power. From this there emerges the pastoral and instrumental character of the Curia. The second part of the article is dedicated to the structure of the Curia, the competences of the curial institutions and their composition and functioning. Finally, some curial institutions are taken into consideration, highlighting in their regard specifications and innovations.